Date of Award

5-1-2024

Degree Name

Master of Science

Department

Biomedical Engineering

First Advisor

Kagaris, Dimitrios

Abstract

This study investigates the applicability of the statistical methods in relation to cancer research aiming to extract critical genes from a diverse range of data sets. The metrics evaluated in this paper are the area-under-the-curve, the partial-area-under-the-curve, the partial-recall-curve, the Cucconi test, and the Jensen-Shannon divergence. Through comprehensive analysis this paper reveals strengths and limitations of each of the different metrics in the context of gene expressions, providing insight for future research. The findings underscore the significance of metric selection tailored to clinical goals.

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