This excel workbook contains data from toxicokinetic studies of two pyrethroid resistant clades of Hyalella azteca (Mosher Slough & Escondido Creek) exposed to 14C-permethrin under varying temperature (18, 23 and 28°C) and salinity (0.2, 1.0 & 6.0 practical salinity units [psu]) conditions. Juvenile Mosher Slough & Escondido Creek H. azteca were exposed to 14C-permethrin at a nominal concentration of 400 ng/L for 36 hours at the aforementioned temperatures and salinities. Individuals were removed after 3, 6, 12, 16, 24 and 36 hours and analyzed for total permethrin and metabolites. The uptake, biotransformation and elimination of permethrin in the H. azteca was determined assuming a two-compartment model (water and H. azteca) and first-order kinetics for uptake, biotransformation, elimination of parent permethrin and biotransformation products (metabolites). Further methodological details can be found in Derby et al., (2020, In Press).
not applicable (lab study)
Hyalella azteca, Menidia beryllina
Toxicokinetics; Hyalella azteca; bioconcentration; permethrin; climate change