Abstract
Children who experience abuse or witness it are at an elevated risk of becoming either victims themselves or engaging in violent behavior later in life, possibly due to the observed behavior of the abuser or the abused. However, socially transmitted aggression remains understudied due to the absence of a suitable behavioral paradigm. This study addresses this gap by introducing a novel social transmission paradigm combined with fiber photometry to explore the brain regions implicated in socially transmitted aggression in mice, given the conservation of their circuity and impact on aggressive behavior. This study addresses this gap by introducing a novel social transmission paradigm combined with fiber photometry to explore the brain regions implicated in socially transmitted aggression in mice. It was imperative to acquire an in-depth comprehension of aggression models utilized in preceding investigations. A thorough examination of multiple publications in the Morris Library database focusing on socially transmitted aggression and early-life stress, specifically employing fiber photometry techniques, was conducted. This literature review facilitated the formulation of a robust model to attain the anticipated outcomes. Notably, the database encompassed articles previously disseminated by the Nordman Lab, serving as pivotal resources for elucidating social transmission models utilized in their prior research. This comprehension was instrumental in devising an animal model capable of representing the nuances of human experiences after instances of aggression and abuse. Through utilization of the resources offered by the Morris Library database, we adeptly devised a rodent model to execute the project with optimal efficiency and effectiveness.
Recommended Citation
Qasem, Elana. "Neural Activation Patterns during Socially Transmitted Aggression." (Spring 2024).