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The project entitled Assessing the Generalizability of Early Life Stress Effects on Aggression aims to enhance our understanding of the intricacies of human aggression associated with childhood trauma. Early life stress is a reliable predictor of aggression in adults. Previous studies have used rodent models to establish a link between early life stress and aggression, but many of these studies employed stressors that are not commonly experienced by humans, such as foot shock. This project intends to focus on more human-relevant stressors like social isolation and social defeat that will provide a better understanding of the brain pathways of human aggression associated with childhood trauma. This research may lead to more targeted clinical interventions.

Abstract

The project entitled Assessing the Generalizability of Early Life Stress Effects on Aggression aims to enhance our understanding of the intricacies of human aggression associated with childhood trauma. Early life stress is a reliable predictor of aggression in adults. Previous studies have used rodent models to establish a link between early life stress and aggression, but many of these studies employed stressors that are not commonly experienced by humans, such as foot shock. This project intends to focus on more human-relevant stressors like social isolation and social defeat that will provide a better understanding of the brain pathways of human aggression associated with childhood trauma. This research may lead to more targeted clinical interventions.

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