Twelve riding horses were utilized to examine the effects of curcumin on intestinal parasites, inflammation, and the fecal shedding of Streptococcus bovis/equinus complex (SBEC), Clostridium difficile and Clostridium perfringens. Known for having anti-inflammatory, antimicrobial, and antiparasitic properties it was hypothesized that curcumin would decrease parasite shedding, inflammation, and opportunistic bacteria found in the GIT of riding horses. Horses were randomly assigned to one of the following treatments (n = 6/treatment): 1) no curcumin, control (CON); or 2) 15 g of 95% pure curcumin, (CUR). Curcumin was dosed per day for 30 d. Fecal samples were evaluated for shedding of ova and concentrations of selected bacteria. Blood samples taken pre and post riding intervals and evaluated for erythrocyte sedimentation rate (ESR) for inflammation. All data were analyzed for repeated measures. Treatment had no effect (P ≥ 0.58) on total fecal egg count, strongyles, or ascarids. Treatment had no effect on ESR (P ≤ 0.42); however, ESR decreased (P = 0.0006) on d 14 in CUR horses. Treatment had no effect (P ≥ 0.34) on concentrations of SBEC, C. difficile, or C. perfringens. Curcumin was not an effective compound against intestinal parasites or fecal microbial strains examined when administered for 30 days; but could potentially decrease inflammation. Curcumin has been observed to have many beneficial effects in other species, however, more research is needed to evaluate those benefits in horses.
Wuest, Samantha, Atkinson, Rebecca L., Bland, Stephanie D. and Hastings, Darcie. "A Pilot Study on the Effects of Curcumin on Parasites, Inflammation, and Opportunistic Bacteria in Riding Horses." Journal of Equine Veterinary Science 57 (Oct 2017): 46-50. doi:10.1016/j.jevs.2017.06.010.