Date of Award

5-1-2011

Degree Name

Master of Science

Department

Electrical and Computer Engineering

First Advisor

Chen, Ada

Abstract

The best way to conquer breast cancer is early detection of the disease. Research studies show that earlier detection results in the increase of life span of the affected person. Traditional two-dimensional mammography is the most prevalent method used in detecting breast cancer. Recently, a three-dimensional digital breast tomosynthesis (DBT) system has been created, which is hopeful to surpass the technology of traditional mammography systems. The DBT system can provide three-dimensional information, allowing physicians to reduce the amount of false negative screening in addition to better monitoring of breast cancer and to catch lesions that may be otherwise cancerous. In this research, the View Angle (VA) and number of projection images (N) were investigated and compared with parallel imaging configurations using two reconstruction algorithms, including Back Projection (BP) and Shift-And-Add (SAA). Modulation Transfer Function (MTF) analyses were conducted with both algorithms, in order to determine which method displayed better image qualities to ultimately improve the detection of breast cancer.

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