The 2011 AAAS "Vision and Change" report has been inspiring undergraduate biology educators nationwide to rethink their educational approach, favoring active learning strategies to better prepare today's students for a complex, data-rich future. Here, we consider the history of the movement, its place in the greater arena of STEM education. and the reasons why this new approach has never been more critical. We encourage all biology educators to consider becoming agents of change, and focus on helpful resources and practical suggestions to help ABT readers take the plunge (or at least get their feet wet) into the welcoming waters of Vision and Change.