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Abstract

Nine plant species belonging to the Euphorbiaceae family and used in traditional medicine in Akwa Ibom State of Nigeria were evaluated for in vitro antimicrobial activity using agar diffusion method. The stem bark of Maesobotrya dusenii gave the most significant effect followed by its root bark. The inhibitory effect of M. dusenii stem bark extract (37 mm) on Pseudomonas aeruginosa was higher than that of Chloramphenicol (35 mm). However, Alchornea laxiflora leaf extract showed the weakest activity. The minimum inhibitory concentration of the extracts ranged between 12.5 and 250 μg/mL. The results of the antimicrobial effects validated the use of the plants to treat infections caused by these microorganisms.

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