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Abstract

The preliminary phytochemical study and in vitro antibacterial activity of the ethanolic extracts of three plants having ethnomedicinal uses collected from tribal belt of Orissa, India, viz. Litsea glutinosa L.: Lauraceae (LG), Vitex peduncularis W.: Verbenaceae (VP), Elephantopus scaber L.: Asteraceae (ES) were investigated. The preliminary phytochemical analysis of the extracts revealed the presence of carbohydrate, tannin, alkaloid in LG, tannin, flavonoid, saponin, alkaloid in VP and flavonoid, saponin, steroid, alkaloid, glycoside in ES. The extracts were subjected for screening of in vitro antibacterial activity against selected major urinary tract infection (UTI) causing pathogens viz. Staphylococcus aureus, Pseudomonas aeruginosa, Proteus mirabilis, Enterococcus faecalis and Escherichia coli at the concentrations of 500 and 250 µg/ml by disc diffusion assay method. The results of antibacterial activity revealed that all the extract showed good inhibitory activity against all the tested pathogens and the ES extract showed comparative by better activity than the other extracts. The activity of the extract were compared with standard antibiotics.

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