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Abstract

Prosopis juliflora DC. is commonly known as "mesquite". This tree is native to tropical America, but is naturalized in many countries including Egypt and India. The preliminary phytochemical screening of the leaves revealed the presence of tannins, acids, glycosides, flavonoids and alkaloids. In vitro antibacterial studies on the ethanolic leaf extracts were carried out on ten medically important bacterial strains (Salmonella typimurium, Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli, Psudomonas sp., Staphylococcus epidermis, Micrococcus luteus, Staphylococcus aureus, Streptococccus sp. and Bacillus subtilis) procured from the Microbial Type Culture and Collection, Chandigarh, India, using the agar disc diffusion method. The bacterial strains were exposed to the following four different concentrations of extracts: 50 mg/ml, 100 mg/ml, 200 mg/ml and 300 mg/ml solvent. The results of our antibacterial assay revealed that the extract showed good inhibitory activity against all the tested pathogens compared with standard antibiotics like streptomycin and penicillin. The inhibitory activities were found to be dose dependent.

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