Abstract

Archaea and eukaryotes, in addition to protein-only enzymes, also possess ribonucleoproteins containing an H/ACA guide RNA plus four proteins that produce pseudouridine (Ψ). Although typical conditions for these RNA-guided reactions are known, certain variant conditions allow pseudouridylation. We used mutants of the two stem-loops of the

Available for download on Saturday, May 29, 2021

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Link to publisher version

http://dx.doi.org/10.1261/rna.073734.119