Drinking water quality is the key factor for sustainability of life and well being of the human population. The quality of water in Texas High Plains generally is suitable for irrigation but doesn’t meet the drinking water standards with respect to certain dissolved constituents (dissolved solids/salinity, fluorides, chlorides and sulfate). Water treatment systems are costly and local communities have financial limitation to afford the required technology. Affordable water treatment facilities with low operating costs are needed to be introduced with an aim to implement cost effective solutions to water management problems. This study focuses on comparing operating costs and cost effectiveness of various drinking water treatment systems. It will serve as a tool to aid local communities’ decision making process to implement cost effective systems. The results will also be helpful in addressing issues pertaining to water management and planning specially for municipal use.