Vitex negundo belongs to the family Verbenaceae. It is a large aromatic shrub distributed throughout the greater part of India up to an altitude of 1500 m in the outer Himalayas. It is widely planted as a hedge plant along the roads and between the roads. Traditionally it is having the flok claims like useful in treatment of rheumatism, insecticidal, antimicrobial, anticancer, tranquillizer, tonic, febrifuge, expectorant and diuretic properties. In the present study an attempt had been made to evaluate comparative antibacterial and antifungal principles from Vitex nigundo with some therapeutically used antibiotics. Different extracts of Vitex negundo leaves were investigated for its anti microbial and antifungal activity on five bacterial species and three fungal species these are Staphylococcus aureus, Proteus vulgaris, Bacillus subtilis, E.coli, Pseudomonas aerugenosa and Aspergillus niger, Aspergillus flavon, Candida albicans respectively. Among all extracts waterethanol (50:50) extract showed maximum anti microbial and water extract showed maximum antifungal activity against all tested species.
Aswar, P. B.; Khadabadi, S. S.; Kuchekar, B. S.; Rajurkar, R. M.; Saboo, S. S.; and Javarkar, R. D.
"In-Vitro Evaluation of Anti-Bacterial and Anti-Fungal Activity of Vitex nigundo (Verbenaceae),"
Ethnobotanical Leaflets: Vol. 2009
, Article 13.
Available at: http://opensiuc.lib.siu.edu/ebl/vol2009/iss7/13