The anti-inflammatory activities of extract of Calotropis gigantea R.Br. and Tridax procumbens Linn., were assessed on carrageenin-induced paw edema along with standard drug, Ibuprofen. The Ibuprofen significantly reduced paw edema at the dose of 200mg/Kg bw orally. The oral administration equi-effective dose (ED50) of C. gigantea (600mg/Kg bw) and T. procumbens (400 mg/Kg bw) individually revealed about 20-35% more activity than the one rendered by administration of 50mg/Kg bw of Ibuprofen. The effect of C. gigantea and T. procumbens along with various dose regimen of Ibuprofen showed greater anti-inflammatory activities than the Ibuprofen alone.
Awasthi, S.; Irshad, M.; Das, M. K.; Ganti, S. S.; and Rizvi, Moshahid A.
"Anti-Inflammatory Activity of Calotropis gigantea and Tridax procumbens on Carrageenin-Induced Paw Edema in Rats,"
Ethnobotanical Leaflets: Vol. 2009
, Article 2.
Available at: http://opensiuc.lib.siu.edu/ebl/vol2009/iss5/2