Ethanolic extracts of the leaves of Rubia cordifolia L. (Rubiaceae) (ERC) were investigated for their phytocompounds, in vitro and in vivo immunopharmacological properties. Immunomodulatory effects of this plant extract were proved in Cyclophosphamide (CP) -induced immunosuppressed animal models. Albino rats were treated with the aqueous extract of ERC and Cyclophosphamide. The Total count (TC) and Differential count (DC) of microphages and blood clotting assay were affected due to the suppressive effect of Cyclophosphamide. Administration of plant extract to CP- exposed animals resulted in enhanced immune responses.
Kannan, M.; Singh, A.J.A.Ranjit; and Narayanan, M.
"Phytochemistry and Ethanopharmacological Studies on Rubia cordifolia Linn. (Rubiaceae),"
Ethnobotanical Leaflets: Vol. 2009
, Article 9.
Available at: http://opensiuc.lib.siu.edu/ebl/vol2009/iss2/9