Dandruff, a clinical condition caused by Malassezia (Pityrosporum) species is of great cosmetic concern all over the world. Dandruff is known to be controlled by fungistatic ingredients in Anti-dandruff shampoos. A comparative study on the efficacy of chemical and herbal anti-dandruff ingredients on ‘as is’ basis and their performance in market shampoos was done in vitro against Pityrosporum ovale (MTCC 1374). Zinc pyrithione (ZnPTO), ketoconazole and other azole compounds recorded good anti-Pityrosporum activity among the chemical ingredients. Herbal ingredients like tea tree oil, rosemary oil, coleus oil, clove oil, pepper extract, neem extract, and basil extract also recorded anti-pityrosporum activity, but their MIC values are much higher than the synthetic ingredients. Shampoos containing ZnPTO and ketoconazole recorded higher in vitro activities than the shampoos containing herbal AD ingredients.
Prabhamanju, M.; Shankar, S Gokul; and Babu, K.
"Herbal vs. Chemical Actives as Antidandruff Ingredients -Which Are More Effective in the Management of Dandruff?– An Overview,"
11, Article 5.
Available at: http://opensiuc.lib.siu.edu/ebl/vol2009/iss11/5