The relationship between angiotensin-converting enzyme (ACE) gene polymorphism and several cardiovascular diseases such as myocardial infarction (MI) and its prognosis is controversial. Clinical evolution, ACE levels, and ACE polymorphism were studied. A control group of 20 valvular patients with normal angiography was established. Angiographic study was done in 50 patients. Our studies reveal that CAD patients with DD genotype of 287 bp ACE gene which is located in the 6th chromosome are under great risk then the DI genotype and II genotype patients of virudhunager, it is as recent with global report .The DD genotype was more frequent in the CAD patient compare to the control the relative risk for DD genotype was high.
Indra, M. and Annapoorani, P.
"Relationship Between the ACE Gene Polymorphism and Angiographic Coronary Artery Disease,"
Ethnobotanical Leaflets: Vol. 2008
, Article 86.
Available at: http://opensiuc.lib.siu.edu/ebl/vol2008/iss1/86