Prediction of Activity Spectra for Substances (PASS), a new computer program, has been generated to evaluate the biological activity of four major flavanoids from a medicinal herb, Boesenbergia pandurata Holtt. (Zingiberaceae). Principal anti-HIV and other biological activities of pinostrobin, pinocembrin, cardamonin and alpinetin were predicted through PASS, their similarity and difference in the mechanisms of action with reference to accessory biological activities have been compared (Tables 1-4) and verified with the available data on pharmacological and toxicological activity of these compounds.
Maridass, Muthiah et al.
"Prediction of Anti-Hiv Activity of Flavanoid Constituents Through PASS,"
Ethnobotanical Leaflets: Vol. 2008
, Article 130.
Available at: http://opensiuc.lib.siu.edu/ebl/vol2008/iss1/130