Sapindus emarginatus Vahl. is extensively used in Indian traditional and folklore medicines to cure various human ailments. The preliminary phytochemical screening of the leaves revealed the presence of saponins, terpenoids, tannins, acids, flavonoids, cardiac glycosides and sugars. In vitro antibacterial studies on the ethanolic leaf extracts were carried out on ten medically important bacterial strains, including Salmonella typimurium, Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli, Pseudomonas sp., Staphylococcus epidermis, Micrococcus luteus, Staphylococcus aureus, Streptococccus sp., and Bacillus subtilis, which were procured from the Microbial Type Cultrue and Collection, Chandigarh, India, using agar disc diffusion method. The bacterial strains were exposed to the following four different concentrations of extracts: 50 mg/ml, 100 mg/ml, 200 mg/ml and 300 mg/ml solvent. The results of our antibacterial assay revealed that the extract showed good inhibitory activity against all the tested pathogens compared with standard antibiotics like streptomycin and penicillin. The inhibitory activities were found to be dose dependent.
Sathiya, M. and Muthuchelian, K.
"Phytochemical Investigation and Antibacterial Screening of Ethanolic Leaf Extract of Sapindus emarginatus Vahl.,"
1, Article 121.
Available at: http://opensiuc.lib.siu.edu/ebl/vol2008/iss1/121