Spathodea campanulata P. Beauv is extensively used in Indian traditional and folklore medicines to cure various human ailments. The preliminary phytochemical screening of the leaves revealed the presence of alkaloids, flavonoids, saponins, tannins, steroids and terpenoids. The organic leaf extracts of this species was evaluated for antimalarial activity against clinically isolated Plasmodium falciparum chloroquine-resistant and sensitive strains. The in vitro antimalarial activity was performed following schizont maturation inhibition assay, (SMI). The ethanol fraction exhibited very good antiplasmodial activity against both chloroquine sensitive and resistant Plasmodium falciparum isolates followed by the butanol and chloroform extracts.
Dhanabalan, Rangasamy et al.
"Preliminary Phytochemical Screening and Antimalarial Studies of Spathodea campanulatum P. Beauv Leaf Extracts,"
1, Article 110.
Available at: http://opensiuc.lib.siu.edu/ebl/vol2008/iss1/110